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27/06/2014

Basler technology contributes to life sciences

Ahrensburg, Germany

Synentec GmbH develops and produces imaging microscopes for fully automatic cell analysis. Nyone is a device that is used primarily in cell research and drug discovery, and the company opted to use Basler camera technology within this new device.

Microscopy is used in medicine primarily for assessing human tissue. In a biopsy or autopsy, for example, the extracted tissue is prepared before the investigation in extremely thin cross-sections or brought into a solution and, if necessary, stained for better depiction of specific features.

Depending on the staining technique used, the filtering of light and the light emitted by the object, different problems can be worked on in the subsequent microscopic examination.

Synentec GmbH develops and produces imaging microscopes for fully automatic cell analysis. Nyone is a device that is used primarily in cell research and drug discovery. Research is important when it is about deciphering the mechanism of a disease. Using the Nyone a detailed look into the interior of cells is possible and every small detail within the cell is resolved. Nyone helps us understand processes within the cell, maps its tracks digitally and converts them into comprehensible data. Image processing and digital cameras are irreplaceable tools in this endeavour.

Tissue or blood samples on a sample holder are stained with fluorescent dyes to produce the microscope images. These dyes bind specifically to the cell or the tissue, thereby facilitating the examination of special areas in or on the cell. Synentec opted for two Basler ace GigE cameras. One of the cameras monitors the optimal position of the object in relation to the sample holder. The second camera is the main camera, delivering the actual microscopic image of the biological sample. A particular feature that impresses is the quality of the camera sensors, and when this is paired with the ability to select specific areas of the image (via AOI) a very high frame rate is generated.

Matthias Pirsch is satisfied with his selection and comments: "Image-based measuring instruments are becoming increasingly important for the life sciences. The quality of Basler cameras is at a level that allows us to replace alternative measuring methods with high-quality imaging systems. Sensitivity and signal quality are the key components on which we rely in Basler cameras. The pylon driver architecture also permits us to make application-specific adjustments quickly and inexpensively and thereby react to market changes rapidly. With Basler we have a partner who copes with complex tasks promptly and reliably and for whom customer service is not an alien concept.”



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